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Archive for the ‘ACOG’ Category

Pap Smears for Women: New Guidelines

Right in the middle of the national firestorm about Mammogram recommendations, the American College of Gynecologists (ACOG) has issued new guidelines for screening of cervical cancer. After 40 years of successfully convincing women to get pap smears annually, the new recommendations say women should not get their first pap test until age 21 and the intervals for testing can then be stretched out.

The new recommendations say that women should start pap screening at age 21 (not teens who are sexually active as previously recommended) and then every two years through age 29. Women age 30 and over with three negative pap smears can stretch it out for three years. Women over age 65 can stop getting pap tests if their previous tests have been negative. Women who have had a hysterectomy for non-cancer reasons never need a pap smear.

The study experts looked at pooled data from around the world. We now know that cervical cancer is caused by certain strains of Human Papillomavirus (HPV), however most women infected with HPV will not develop cervical abnormalities. Most women who contract HPV have an effective immune system that clears the virus. Paps that are done too frequently can show abnormalities that would, in the majority of cases, clear spontaneously.

The researchers also found that pap tests are difficult to interpret and there is inconsistency among cytologists reading the slide. Upon a second review, most results that were reported as showing abnormalities were downgraded to normal.

The study points out that abnormal pap tests lead to a sequence of further testing, biopsies and excisional procedures that can adversely affect a young woman’s reproductive health.

In summary, the new guidelines recommend:

  • Start pap smears at age 21 regardless of prior sexual activity (no need at all in virgins).
  • Test every 2 years to age 30
  • After age 30, test every 3 years if prior tests are normal
  • Stop at age 65 if prior tests have been negative.
  • No paps needed for women who have had hysterectomy if there was no cancer

It is ironic that we now have two significant changes for screening tests in women’s health. According to the chair woman of the ACOG study group, Dr. Cheryl Iglesia, it was a bizarre coincidence that their guidelines hit right at the same time as the mammogram controversy.

The 12 page recommendations from ACOG can be found here.

*This blog post was originally published at EverythingHealth*

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My Take On The Mammogram Issue

I was having an interesting Twitter chat with online friends (Liz Cohen @elizcohencnn, Dr. Chuk Onyeije @chukwumaonyeije; Dr. David Gorski @gorskon; Dr. Marya Zilberberg @murzee; Sherry Reynolds @cascadia; and @speakhealth) about the mammogram debate. They asked me “where I drew the line” on paying for expensive screening tests that may save lives but require unnecessary surgery for countless others. My opinion takes into account human nature and political savvy rather than pure science and statistics on this one.

To me, the bottom line is that the mammogram is a sloppy screening test. It’s expensive, there are lots of false positives and unnecessary surgeries, yet it saves occasional lives (which is dramatic and meaningful). We have to appreciate that women have come to accept the risks/benefits of this test, and have been told for a long time that they should begin screening at age 40.

It’s not emotionally or politically possible to reverse course on this recommendation until a better choice is available. You can trade the mammogram for a better test, but you can’t trade it for doing nothing. The amount of drama associated with the perception of having something potentially life-saving taken away is just not worth the cost savings. It may be a reasonable value judgment based on the data, but it’s not politically feasible so we should mentally take it off the table.

Instead we must focus on the search for a better test - something that’s more accurate and less expensive. We will be stuck paying for lots of unnecessary mammograms/biopsies for now, no way around it. But let’s think of it as a temporary predicament - not an eternal waste of resources.

In the end, women should have a nuanced conversation with their doctor about whether or not they are at risk for breast cancer, and make an informed personal decision about when to begin mammography screening. Guidelines are not mandates - though the USPSTF’s well intentioned report would probably have been better left unwritten.

Now let’s fund some serious research into a better screening test!